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Methodologies
Instrumental Analytics
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- HPLC (refraction index, fluorescence and diode array detection)
- Capillary electrophoresis (diode array detection)
- Dissolution testing
In-capillary reactions
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- Enzymatic reaction kinetics using capillary electrophoresis
Caco-2 model
PAMPA model
In vitro permeability and transport models
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- PAMPA model
- Bidirectional Caco-2 model
Cytotoxicity
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- MTS/MTT
Protein Characterization
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- SDS-PAGE
- Western immunoblot
Whole-cell assays development
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- Spectrophotometric assays
- Fluorimetric assays
- In-gel activity assays
PHARMACOKINETICS AND BIOPHARMACEUTICAL ANALYSIS
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